Researches Projects carried out in this department t
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• HLA-DRB1 specific siRNA in RA treatment.
• HLA-DRB1*0405 transgenic mice modle.
• Epidemiology of RA
• Combination examination of multi-autoantibodies in autoimmune disease diagnosis.
• Regulatory role of altered type II collagen peptide in HLA-DRB1 mediated autoimmune disease.
• Function of cyclic citrullinated peptide in RA pathogenic mechanism.
• Intracellular expression of altered type II collagen peptide and its therapeutic effects in experimentally induced arthritis .
• T cell immunotherapy in systemic lupus erythematosus.
• Study of recombinant alpha fordrin protein expression and its function in Sjogren's syndrom pathogenesis.
• Study of HLA-DRB1 restricted peptide in RA therapy.
• Molecular mechanism of HLA-DRB1 restricted peptide in RA pathogenesis.
• Screening of alpha fordrin protein T cell epitope and its clinical significance.
• Significance of M3 and its antibody in Sjogren's Syndrome pathogenesis and diagnosis
• P68 and its function in RA pathogenesis.
• Construction of RA synovial tissue cDNA T7 phage display library
• Screening and identification of novo antigen in RA.
• Enternacept in RA treatment.
• Function of nucleosome in SLE pathogenesis.
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